I would always lay it out in front of me to get the best design before I started sewing. I also kept in mind that I didn't want too many repeats, so I tried to make it different every time.
I started out by taking each bundle of six and sewing it together in threes. I would do three or four bundles at a time so I could whip more through my machine at once. You just need to be careful not to mix up your piles, I wouldn't do more then 4 bundles at a time.
Try to mark your fabrics or just be careful to keep the pairs together. You can even safety pin them if you transport them a lot.
Now it was time to sew my rows together. It's nice to have your sewing machine close to where your quilt is laid out. I would do one row at a time but would reference back to my design a lot. I have sewed hexagons together and it is much easier doing it in the rows.
I love the one block wonder!!! It's sometimes very hard to match up fabric when making a traditional quilt, for this quilt bang! it matches, and every hexagon is different and unique. It's truly one of a kind. My quilt ended up being 5 hexagons by 7 hexagons or 32x46, so I definitely need to add some borders. But from 2 yards of fabric this ain't bad, and I have enough to add a 1 or 2 inch border as well.
For next time... I learned from doing this one that I might not iron so that I can manoeuvre my fabric better and just let it fall into place as I go. Oh and have more fabric :) I actually have my next one all planned out and bought 6 panels to see how that will work. It's a really pretty Michael Miller fairy panel, almost a shame to cut it up.